WebFAM134B Attenuates Seizure‑Induced Apoptosis and Endoplasmic Reticulum Stress in Hippocampal Neurons by Promoting Autophagy Nanchang Xie 1 · Yingjiao Li 1 · Cui Wang 2 · Yajun Lian 1 · Haifeng Zhang 1 · Yujuan Li 1 · Xianghe Meng 1 · Liyuan Du 1 WebDec 16, 2024 · The Fam134b gene, located on chromosome 5p15.1, was first identified as a regulator of the malignant phenotype and a downstream molecule of δ-catenin in esophageal squamous cell carcinoma (Tang et al., 2007). However, in colon cancer, FAM134B inhibits the migration of tumor cells (Kasem et al., 2014a, b).
FAM134B (E8Y9R) Rabbit mAb Cell Signaling Technology
Highly specific and rigorously validated in-house, FAM134B (E8Y9R) Rabbit Monoclonal Antibody (CST #83414) is ready to ship. ... FAM134B (family with sequence similarity 134, member B), also referred to as JK-1 and RETREG1, is a cis-Golgi endoplasmic reticulum (ER) transmembrane protein that plays a role in ER homeostasis and may contribute to ... Webanti-LC3B (1:200; CST, USA; #83506) and rabbit anti-FAM134B (1:100; Abcam, USA; ab151755) overnight at 4 °C. Subsequently, the neurons were incubated with dye … open loop vs closed loop op amp
FAM134B Attenuates Seizure-Induced Apoptosis and …
WebFeb 19, 2024 · FAM134B was the first and so far the best characterized ER-phagy receptor (Khaminets et al, 2015). FAM134B is an intramembrane ER-resident protein that contains a LIR domain and a reticulon homology domain (RHD), which consists of two membrane-embedded hydrophobic regions bridged by a flexible cytoplasmic linker ... WebDec 14, 2024 · FAM134B has also been associated with different cancers, although its exact role remains elusive. We report here that the FAM134B gene encodes not one but … WebJun 3, 2015 · These data demonstrate that FAM134B is an ER-anchored autophagy receptor that mediates ER delivery into lysosomes through sequestration into autophagosomes (ER-phagy). Notably, this … ipad can\u0027t delete keyboard shortcuts