WebIndications. GAZYVA ® (obinutuzumab) is a prescription medicine used in combination with chemotherapy, followed by GAZYVA alone in those who responded, to treat stage II bulky, III, or IV follicular lymphoma (FL) in adults who have not had previous FL treatment. GAZYVA ® (obinutuzumab) is a prescription medicine used with the chemotherapy ... Webdose ramp-up schedule • The VENCLEXTA starting dose is 20 mg once daily for 7 days, ramping up weekly to 50 mg,100 mg, 200 mg, and finally 400 mg once daily • After completing the ramp-up schedule on Cycle 2, Day 28, patients should continue VENCLEXTA 400 mg once daily from Cycle 3, Day 1 until the last day of Cycle 12 …
Obinutuzumab FDA - U.S. Food and Drug Administration
WebDec 28, 2024 · 1. How it works. Gazyva is a brand (trade) name for obinutuzumab which may be used to treat or delay the progression of chronic lymphocytic leukemia and follicular lymphoma. Gazyva works by targeting a specific antigen called CD20 which is a type of protein found on normal and cancerous B-lymphocytes. WebJun 9, 2024 · You will receive a dose of Gazyva on days 1, 2, 8, and 15 of your first cycle. Below is the Gazyva dosing schedule for the first cycle of treatment: Day 1: 100 mg. … old texas instruments computer
Venetoclax: MedlinePlus Drug Information
WebMay 13, 2014 · Obinutuzumab (Gazyva), manufactured by Genentech, is a novel anti-CD20 monoclonal antibody FDA approved, ... On day 1 of cycle 1, a dose of 100 mg should be administered at 25 mg/h over 4 hours, and the infusion rate should not be increased. On day 2 of cycle 1, 900 mg should be administered at 50 mg/h, and the infusion rate may … WebJun 4, 2024 · Week 1: 20 mg orally once a day. Week 2: 50 mg orally once a day. Week 3: 100 mg orally once a day. Week 4: 200 mg orally once a day. Week 5 and beyond: 400 mg orally once a day. MONOTHERAPY: Start after the patient has completed the 5-week dose ramp-up schedule: 400 mg orally once a day until disease progression or unacceptable … WebThe recommended dose and schedule for the regimen follows: Obinutuzumab: 1000 mg by intravenous infusion on days 1, 8 and 15 of cycle 1; on day 1 of cycles 2-6 (28-day … old texas logos