Hu-binding site
HU is able to bind all forms of nucleic acids, including DNA–RNA hybrids (Balandina et al., 2002). Although HU has no specific binding motif, it is able to bind mRNA of RpoS (Balandina et al., 2001). Another study of the B. subtilis HU protein showed that HU binds an Alu domain of cytoplasmic RNA (Nakamura et al., … See more In 1975, a small, low-molecular-weight DNA-binding protein was isolated from E. coli strain U13 (Rouvière-Yaniv and Gros, 1975). At first, it was referred to as Factor U. Due to its … See more HU protein is among the most abundant and conserved nucleoid-associated proteins in eubacteria (Azam and Ishihama, 1999). The greatest abundance of HU protein has … See more Interaction of HU protein at protein level has not yet been fully explored. As mentioned above, an HU protein is able to react with another HU protein to form a dimer together … See more HU seems to be an important protein for DNA compaction, replication, transcription, recombination, and shape modulation in many bacteria (Broyles and Pettijohn, 1986; Roy et al., 2005; Oberto et al., 2009). In the coccoid … See more Initially, bacterial DNA binding proteins were thought to help stabilize bacterial DNA. Currently, many more functions of bacteria DNA binding proteins have been discovered, including the regulation of gene expression by histone-like nucleoid-structuring protein, H-NS. H-NS is about 15.6 kDa and assists in the regulation of bacterial transcription i…
Hu-binding site
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Web19 Mar 2024 · The PWSM has been successfully used in the prediction of transcription factor binding sites and ligand binding sites (Kel et al., 2003; Hu et al., 2016a). Thus, the position weight scoring matrix (PWSM) was used to extract the position conservation information of the basic feature parameters, and the scoring matrix based on amino acid …
WebThe binding sites in c-Fos, interleukin-3, c-Myc, Tau, IVA 2 , and GAP-43 mRNAs are shown. ... Neuronal ELAV/Hu (nELAV) are RNA-binding proteins that mainly regulate … Web7 Apr 2024 · ELAV/Hu RNA binding proteins determine multiple programs of neural alternative splicing - PMC Back to Top Skip to main content An official website of the United States government Here's how you know The .gov means it’s official. Federal government websites often end in .gov or .mil.
Web2 Sep 2013 · The HU protein bends DNA at low protein concentrations, promoting compaction, and stiffens DNA at high concentrations (supplementary figure S1). (6-8) The affinity of HU for short regular B-DNA substrates is in the micromolar range, whereas affinities in the nanomolar range have been reported for binding to pre-distorted DNA … Web30 Aug 2024 · The identification of metal ion binding sites is important for protein function annotation and the design of new drug molecules. This study presents an effective …
Web1 Mar 2008 · HU binding to ssDNA, dsDNA and nick in low salt conditions. HU protein, at the concentration indicated in nM on the bottom, was mixed with end-labeled DNA, 40-bp long dsDNA, the same DNA with a ...
Web23 Dec 2008 · Gene expression is potently regulated through the action of RNA-binding proteins (RBPs) and microRNAs (miRNAs). Here, we present evidence of a miRNA regulating an RBP. The RBP HuR can stabilize and modulate the translation of numerous target mRNAs involved in cell proliferation, but little is known about the mechanisms that … cyberlink subscriptionWebHU, a major component of the bacterial nucleoid, shares properties with histones, high mobility group proteins (HMGs), and other eukaryotic proteins. HU, which participates in many major pathways of the bacterial cell, binds without sequence specificity to duplex DNA but recognizes with high affinity DNA repair intermediates. cyberlink supportWeb1 Dec 2000 · Introduction. Escherichia coli HU, a small, basic, heat-stable DNA binding protein, is one of the most abundant proteins associated with the E.coli nucleoid (Rouviere-Yaniv and Gros, 1975; Rouviere-Yaniv, 1978). In vitro, HU shares the ability observed with histones to introduce negative supercoiling into relaxed DNA molecules in the presence … cyberlink streamingWebHu Proteins Block Binding of CstF64 to Poly(A) Sites and Interact with Two Polyadenylation Factors—To probe the mechanism whereby Hu proteins inhibit … cyberlink stock photosWeb不废话，先介绍和使用教程，后面讲讲体验后的优缺点 背景. Claude是一支由前openai的研究员和工程师组成的团队开发的新型聊天机器人，旨在对抗chatgptClaude的特点是能够检测和回避chatgpt的潜在陷阱，如逻辑错误、不恰当的内容、重复性和无聊等。 cheap maseratis for saleWeb1 Aug 2011 · The Hu proteins (HuA/R, HuB, HuC, and HuD) are a family of mammalian RNA-binding proteins. Of the four Hu family members, HuA/R is widely expressed in … cyberlink stop motion editingWebHU binding site and present evidence that protein-protein in- teractions do not mediate this high affinity binding. Further- more, we report that the mammalian HMG-1 protein … cyberlink sucks