Phosphopantetheine adenylyltransferase
WebApr 15, 1999 · Phosphopantetheine adenylyltransferase (PPAT) is an essential enzyme in bacteria that catalyses a rate-limiting step in coenzyme A (CoA) biosynthesis, by transferring an adenylyl group from ATP to 4′-phosphopantetheine, yielding dephospho-CoA (dPCoA). Each phosphopantetheine adenylyltransferase (PPAT) subunit displays a dinucleotide … WebINIS Repository Search provides online access to one of the world's largest collections on the peaceful uses of nuclear science and technology. The International Nuclear Information System is operated by the IAEA in collaboration with over 150 members.
Phosphopantetheine adenylyltransferase
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Webpantetheine-phosphate adenylyltransferase Synonyms 3′-dephospho-CoA pyrophosphorylase PPAT dephospho-CoA pyrophosphorylase dephospho-coenzyme A pyrophosphorylase pantetheine phosphate adenylyltransferase Additional information <3, 4> (<3,4> with EC 2.7.1.24 part of a bifunctional enzyme with EC 2.7.1.24 [4,5]) [4, 5] CAS … WebJan 25, 2002 · Introduction. Phosphopantetheine adenylyltransferase (PPAT) catalyzes a key regulatory step in the coenzyme A (CoA) biosynthetic pathway: 1 the reversible transfer of an adenylyl group from ATP to 4′-phosphopantetheine (Ppant), which yields 3′-dephospho-CoA (dPCoA) and pyrophosphate. 2 CoA biosynthesis occurs in a series of …
WebMar 24, 2010 · To identify the phosphopantetheine adenylyltransferase sub-site bound by these inhibitors, two techniques were utilized: steady-state enzyme kinetics and a novel 19 F NMR method in which fluorine-containing fragments that bind the ATP and/or phosphopantetheine sites serve as competitive reporter probes. These data are … WebMay 30, 2024 · In this study, phosphopantetheine adenylyltransferase (PPAT/CoaD) enzyme, involved in the coenzyme A biosynthesis pathway, was evaluated in the context of fragment-based discovery of new inhibitors targeting Mycobacterium abscessus. The structures of PPAT from M. abscessusMab PPAT, facilitating the initiation of a structure …
WebPhosphopantetheine It is known as phosphopantetheine adenylyltransferase (PPAT; EC 2.7.7.3) or as the CoaD protein. From: Comprehensive Natural Products II, 2010 Peptide … WebJan 25, 2002 · Phosphopantetheine adenylyltransferase (PPAT) catalyzes a key regulatory step in the coenzyme A (CoA) biosynthetic pathway: 1 the reversible transfer of an …
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WebPhosphopantetheine adenylyltransferase (PPAT) regulates the key penultimate step in the essential coenzyme A (CoA) biosynthetic pathway. PPAT catalyzes the reversible transfer … popcorn katy texasWeb7.11.3.6 Phosphopantetheine Adenylyltransferase (coaD Gene Product) The penultimate CoA biosynthetic enzyme catalyzes the reversible Mg 2+-dependent adenylylation of 4′ … popcorn kernel clipart black and whiteWebOct 3, 2001 · Phosphopantetheine adenylyltransferase (PPAT) is an essential enzyme in the coenzyme A pathway that catalyzes the reversible transfer of an adenylyl group from ATP … sharepoint online calendar listWebpantetheine adenylyltransferase (PPAT), which catalyzes the penultimate step in the pathway (Fig. 1), the reversible adeny-lation of 49-phosphopantetheine to form 39 … sharepoint online calendar tags and notesWebPhosphopantetheine Adenylyltransferase (PPAT) is an enzyme that catalyzes the penultimate step in the biosynthesis of Coenzyme A (CoA), which is the active and … sharepoint online cannot change welcome pageWebApr 4, 1999 · Phosphopantetheine adenylyltransferase (PPAT) is an essential enzyme in bacteria that catalyses a rate-limiting step in coenzyme A (CoA) biosynthesis, by transferring an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA). sharepoint online calendar optionsWebAug 31, 2015 · Inside the cell, 4′-phosphopantetheine was enzymatically converted back to CoA by the bifunctional enzyme CoA synthase. Phenotypes induced by intracellular CoA deprivation were reversed when... popcorn kernel and seasoning gift set